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DNT 53™ Capsules Overview:

At present, there is an intense need & demand for effective formulation which can facilitate treatment of Thrombocytopenia (Low Platelets count).

Thrombocytopenia affects 44% to 96% of patients with co-morbid conditions. It leads to an increased risk of life threatening bleeding which needs emergency hospitalization. At present the most common treatment of Thrombocytopenia is Platelet Transfusion, Immunoglobulins, immunosuppressive agents & surgical removal of Spleen.

DNT 53™ Capsules are clinically proven, safe and herbal formulation for Thrombocytopenia which contains blend of various herbs. Each herb present in this formulation is scientifically proven and mentioned in the Ayurvedic Pharmacopoeia of India, approved by Government of India.

DNT 53™ Capsules are scientifically developed formulation which increases platelet counts as rapid as day 3 of consuming it. A Govt. certified Lab conducted a clinical study to evaluate its efficacy & safety. DNT 53™ Capsules has shown significant increase in platelet count throughout the study when compared to screening platelet level in all enrolled subjects. During the study they did not find any adverse effect related to safety of the DNT 53™ Capsules.

Toxicity Study Conclusion:

In the study there were no clinical signs and pre terminal death noted at and up to the high dose of 1000mg/kg body weight. There were no dose dependent statistical significant treatment related adverse effect on body weight, food consumption, organ weight, hematology and clinical chemistry parameters of animal at and up to the dose of 1000mg/kg body weight. There were no gross external or internal pathological changes noted at any dose level. There were no treatment related histopathological changes noted at dose level of 1000mg/kg body weight.

Hence from the study it can be concluded that No-Observed Adverse Effect Level (NOAEL) of DNT 53™ Capsules administered through oral route daily consecutively for 28 days was in Sprague-Dawley rats was found to be 1000mg/kg body weight.

Clinical Study Conclusion

All 72 enrolled subjects were advised to take study drug as protocol prescribed and they were advised to attend every alternate day visits to the site. The data has been collected and analyzed from 72 subjects who have completed all study visits and it was found that there was significant increase in platelet count irrespective of group.

We analyzed group wise platelet count and found that the platelet count was significantly increased in all subjects in all mentioned group.

There was no drop out subjects during the study.

From the data obtained, it was found that the investigational product DNT 53™ Capsules was showing significant percentage increase in platelet count throughout the study duration when compared to screening the platelet level in all enrolled subjects, which was considered as an important parameter in the study.

DNT 53 Capsules FAQs:

Ans.: Platelets are small disc shaped blood cells produced in the bone marrow that plays very important role in the process of Blood clotting. The normal range is between 150,000- 450,000 platelets in each microliter of blood. Low platelet counts or abnormally shaped platelets are closely associated with bleeding disorders.

Ans.: Thrombocytopenia is the medical term for a condition in which platelet count decreases in the blood below the normal range.

Ans.: DNT 53™ Capsules is a clinically proven unique mixture of herbs and it is indicated as an adjunct for the management of thrombocytopenia. All the herbs used in DNT 53™ Capsules are mentioned in THE AYURVEDIC PHARMOCOPEIA OF INDIA.

Ans.: DNT 53™ Capsules are a blend of pure herbs with high medicinal properties and is beneficial in managing low blood platelet counts in adults.

Ans.: Yes, DNT 53™ Capsules will bring your platelet counts to normal levels after completing the course of medication, although increase in platelets counts can be seen as early as within one to two days after starting the medication.

Ans.: DNT 53™ capsules are to be administered orally 3 to 4 times a day or as directed by Physician.

Ans.: Yes, DNT-53 Capsules are clinically proven Ayurvedic formulation. The clinical study to evaluate the efficacy and Safety of DNT -53 Capsules in patients with low platelet count has been completed by a Government approved clinical trial organization.

Ans.: During toxicity and clinical trial, no adverse effect was seen in any subject. Hence DNT 53™ Capsules have no associated side effect.

Ans.: Your healthcare provider will check your platelet count every week and change the dose of DNT 53™ Capsules accordingly.

Ans.: Keep the container tightly closed & protect from direct sunlight and moisture.

Ans.: Yes, DNT-53 Capsules clinical research is published in the following journals.

  1. Novus International journal of biotechnology & biosciences-2013, Volume 2, Number 3 INTERNATIONAL STANDARD SERIAL NUMBER: 2278-6945
  2. Deccan Pharma Journals January – February 2014 INTERNATIONAL STANDARD SERIAL NUMBER: 0976-139X
  3. Trendz in Biotech volume 12/Issue 12/ March 2014. INTERNATIONAL STANDARD SERIAL NUMBER: 0975-4369

  1. DNT 53™ Capsules should not be taken empty stomach.
  2. DNT 53™ Capsules should not be consumed in pregnancy, during lactation & children below 15 years.

Ans.: While consuming DNT 53™ Capsules patients can take both vegetarian & Non-Vegetarian Diet.

Ans.: While having DNT 53™ Capsules, if the patient is suffering from any other ailment he/she can take any other medicines as prescribed by the concerned Doctor, without discontinuing the DNT 53™ Capsules provided that a gap of half an hour is given between these two.

Ans.: DNT 53™ Capsules should not be taken in the morning on an empty stomach. If there is any difficulty in swallowing the capsule, the contents of the capsule can be mixed in milk or honey and then taken.

Ans.: Total course of DNT 53™ Capsules is 10 days or as directed by the physician.

Ans.: Yes, DNT 53™ Capsules are suitable for vegetarian. DNT 53™ Capsules is supplied in cellulose capsule – a 100% vegetarian source.

Ans.: DNT 53™ Capsules come in HDPE bottle with child lock which contain 34 Capsules.